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While the smoking of marihuana is rather widespread among the intellectually and emotionally immature population concentrated in the vicinity of Harlem, the Mayor's Committee on Marihuana finds little cause for alarm. The addict knows when he has had enough and refuses an overdose. He does not crave the drug and shows no withdrawal symptoms, relatively little elevation in tolerance, even after a decade of constant use, and little tendency to lapse into severe alcoholism, morphinomania, crime or sexual excesses. The addict employs it for the purpose of enjoying a quiet sociability, with lowered inhibitions and free-ranging philosophic speculations, which are actually on a very superficial level. Mental and emotional deterioration are not demonstrable. This is not to say that there are no toxic properties in marihuana. Acute intoxication can result from overdosage, and psychotic states may follow acute intoxication, but these clear up within a few days.
The Mayor's Committee,
The Marihuana Problem in the City of New York. Sociological, Medical, Psychological and Pharmacological Studies. Arch NeurPsych. 1946;55(1):77. doi:10.1001/archneurpsyc.1946.02300120087011
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