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February 1946

HISTOLOGIC CHANGES IN THE BRAIN IN CASES OF FATAL INJURY TO THE HEAD: VII. ALTERATIONS IN NERVE CELLS

Author Affiliations

LOS ANGELES

From the Neurosurgical Service and the Cajal Laboratory of Neuropathology, Los Angeles County General Hospital; the Department of Surgery (Neurosurgery), University of Southern California School of Medicine, and the Department of Nervous Diseases, College of Medical Evangelists.

Arch NeurPsych. 1946;55(2):79-110. doi:10.1001/archneurpsyc.1946.02300130003001
Abstract

In a series of studies concerned with pathologic changes in the various cytologic elements of the brain following injuries to the head, of which this study constitutes a unit, we have kept two objectives in view. The first, and perhaps the most important, has been an attempt to explain the residual symptoms which so often persist after an injury to the head. The second, and more academic, objective was an attempt to discover the finer details of such alterations which occur in these various elements as a result of cranio-cerebral trauma. By a study of such changes it was hoped to shed some light on the biologic behavior of these cells and fibers in response to physical injury. As these studies have drawn to a close, it has become evident that we have been more successful in the attainment of the second than of the first of these objectives. In

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