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July 1946

Klinische und erbbiologische Untersuchungen über die Heredoataxien.

Arch NeurPsych. 1946;56(1):130-131. doi:10.1001/archneurpsyc.1946.02300180142017

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Sjögren has long been known to students of heredity in relation to neurologic disorders, having had abundant opportunities for genetic investigations in the relatively stationary population of Sweden. His industry in the assembling of data in the present large investigation is noteworthy, and his mathematical handling of the material is commendable, if somewhat beyond the scope of the average neurologist. This volume comprises a study of 188 cases of the heredoataxias, occurring in 118 families, and investigations covering a total of 3,111 persons. Cases occurring in family groups are reported, and maps are appended to show the geographic relationships. The present observations are not so striking as were those in the author's previous studies on Huntington's chorea, in which parish records indicated the inheritance of the disease through as many as nine generations. In the present investigation the disease was traceable through five generations. From his study, in which records