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February 1947

VOLUME FLOW OF BLOOD THROUGH THE HUMAN BRAIN

Arch NeurPsych. 1947;57(2):137-144. doi:10.1001/archneurpsyc.1947.02300250015001
Abstract

VALID quantitative data on the volume flow of blood through the human brain are of crucial importance for the solution of a variety of clinical and theoretic problems. The poverty of such data has been due chiefly to a lack of suitable technics. The thermoelectric flow recorder devised by one of us (F. A. G)1 does not yield qualitative data unless calibrated in situ, and this has not been done in man. Ferris2 has employed a method by which the bone-supported dural coverings of the brain and spinal cord are used as a plethysmograph. A trochar is inserted into the lumbar sac, and with an inflatable cuff the veins of the neck are compressed. The cerebral blood flow is estimated from the rate of displacement of spinal fluid. Kety and Schmidt3 have recently described a method based on the principle that the rate at which the brain

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