THE VALUE of insulin in treatment of certain mental diseases has been proved beyond doubt, even though a long term evaluation of the results suggests that the therapeutic effects are better in the way of producing remissions than actual cures. Most experiences recorded in the medical literature have to do with insulin shock rather than with subshock or subcoma technic. A number of investigators1 have shown that with insulin shock treatment the rate of remission is from three to five times the so-called spontaneous rate of remission and that the rate of prolonged remission is about twice the rate of prolonged spontaneous remission. During the first years of insulin shock therapy it was hoped that the apparent recoveries would hold for an indefinite period, but subsequent follow-up observations have shown that what had appeared originally to be recoveries were only remissions. These results are further influenced by the duration
SULLIVAN DJ. INSULIN SUBSHOCK (SUBCOMA) TREATMENT OF PSYCHOSES AND PSYCHONEUROSES. Arch NeurPsych. 1948;59(2):184–214. doi:10.1001/archneurpsyc.1948.02300370046002
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