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April 1948


Author Affiliations


From the Mercy Hospital-Loyola University Clinics.

Arch NeurPsych. 1948;59(4):504-510. doi:10.1001/archneurpsyc.1948.02300390061008

IN RECENT years a number of reports have appeared of a condition variously designated as the Sturge-Weber syndrome, Kalischer-Dimitri disease or Brushfield-Wyatt disease. All these terms apparently refer to the same clinical entity. The condition is one of associated facial nevus with homolateral glaucoma and an intracranial pathologic process in the form of angiomatous changes, sometimes in the pia mater and at others in the cerebral cortex itself. As a rule calcium deposits of one type or another are seen. The pathologic changes in the brain are usually manifested by epileptic seizures, feeblemindedness or visual field defects, the last-mentioned symptoms appearing when the occipital lobes are involved, as its often the case. Nussey and Miller1 stated that it was Schirmer2 in 1860, who first described a patient displaying an associated facial nevus and glaucoma. A few years later, in 1870, Sturge3 recorded a case of nevus of

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