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May 1948

Cerebral Angiography with Perabrodil (Carotid Angiography).

Arch NeurPsych. 1948;59(5):685. doi:10.1001/archneurpsyc.1948.02300400121012

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Perabrodil is an organic iodine compound that can be used safely in the delineation of the cerebral vessels. Angiography has become such an important method of diagnosis of intracranial lesions that every neurologist should have a reasonable acquaintance with this subject. Not infrequently the arteriogram is more valuable than the encephalogram or the ventriculogram, for it reveals not only the location of the disease process but also its nature. In a case of rapidly expanding intracranial lesion, for instance, the arteriogram can distinguish abscess, hematoma and gliobastoma multiforme. Subarachnoid hemorrhage from aneurysm can be differentiated from that due to angiomatous malformations and can guide the surgeon in his surgical attack. By indicating the principal source of blood supply in certain tumors, the angiogram can point the way to satisfactory control of hemorrhage at the time of operation.

Whether the contrast medium is injected into the exposed artery or whether it