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December 1948

"INVERTED MARCUS GUNN PHENOMENON": (So-Called Marin Amat Syndrome)

Author Affiliations


From the Division of Neurology, University of California Medical School.

Arch NeurPsych. 1948;60(6):584-596. doi:10.1001/archneurpsyc.1948.02310060037004

THE ASSOCIATED movement between the jaw and the upper eyelid described first by the London ophthalmologist Marcus Gunn in 1883 evoked great interest among neurologists and ophthalmologists. There have been many publications on this subject, even in recent years. This phenomenon, usually called jaw-winking phenomenon, consists of automatic, involuntary, irresistible lifting of the ptotic eyelid when the mouth is opened, and particularly when the mandible is moved to the side opposite the ptosis. Of the numerous modifications of the original Marcus Gunn phenomenon described in the voluminous international literature, the so-called inverted Marcus Gunn phenomenon is of great physiologic interest. In this condition, on movement of the mandible, not a lifting of the eyelid but a closure of the eye occurs.

Since the phenomenon of Marcus Gunn has been so often observed and thoroughly investigated, one is from the very outset justified in being skeptical of the existence of the

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