THE MANY and varied concepts of defects, or agenesias, of the corpus callosum will be easily understood by a comparison of two recent papers on this subject. De Morsier and Mozer1 suggested as an etiologic factor a disturbance during the closure of the anterior neuropore, as had previously been proposed by Marchand,2 Goldstein3 and Ernst.4 De Morsier and Mozer1 described a second type, in which an embryonal neoplastic agent, a lipoma or an angioma, destroys the corpus callosum (callosal body) during fetal life. Eventually, they claimed that disturbances in the vascularization of the lamina terminalis by the anterior callosal artery during fetal life was another cause. Kirschbaum,5 on the contrary, suggested porencephaly as a cause of agenesia of the corpus callosum, whereby, in agreement with Yakovlev and Wadsworth,6 an agenesia of the gyrus cinguli is the causative factor.
In my paper presented at
MARBURG O. SO-CALLED AGENESIA OF THE CORPUS CALLOSUM (CALLOSAL DEFECT): Anterior Cerebral Dysraphism. Arch NeurPsych. 1949;61(3):297–312. doi:10.1001/archneurpsyc.1949.02310090072007
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