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October 1949


Arch NeurPsych. 1949;62(4):439-444. doi:10.1001/archneurpsyc.1949.02310160059004

ACCORDING to Dandy,1 "one can hardly expect to cure multiple abscesses by surgical means unless they are contiguous and limited to two or three in number." Kahn2 stated that metastatic abscesses are due to either pleuropulmonary infections or generalized pyemia, that they are usually due to anaerobic organisms and do not encapsulate and that in his hands the outcome has invariably been fatal. Coleman3 wrote that metastatic abscesses rarely yield to surgical treatment because of the serious systemic infection preceding their development and the multiplicity of the lesions. King4 stated, "It is granted that there is no likelihood of recovery following operation in cases of multiple abscesses of the brain." These statements were for the most part made prior to the advent of chemotherapy and the use of antibiotics. In 1946, I5 reported my early experiences with penicillin in the treatment of brain abscess and