ONE OF the problems in physiology has been the identification of areas in the cerebral cortex which modify activity of the autonomic nervous system. In view of the striking changes which take place in autonomic activity as a result of emotion, it is logical to assume that such areas are present. As a result of experimental work on animals and clinical observations on man, at present there appear to be four areas of the cerebral cortex which play a role in the regulation of autonomic activity. They are the motor areas 4 and 6, the anterior part of the cingulate gyrus (area 24), area 8 of the frontal lobe and the orbital surface of the frontal lobe.1 Lesions of areas 4 and 6 of the cerebral cortex in monkeys and in man are associated with an alteration in vasomotor activity.2 By electrical stimulation of the motor cortex of