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April 1950

EFFECT OF ELECTRICALLY INDUCED CONVULSIONS ON CUTANEOUS LYMPHATIC FLOW

Arch NeurPsych. 1950;63(4):593-595. doi:10.1001/archneurpsyc.1950.02310220060005
Abstract

EARLIER work afforded data which indicated that accelerated flow occurred in cutaneous lymphatics when the amount of tissue fluid increased during the intravenous administration of solutions of electrolytes.1 In view of the fact that fluid is lost from the circulation to the tissues during electrically induced convulsions,2 it was considered of interest to study the behavior of the lymphatics of the skin before and after such seizures.

MATERIAL AND METHODS  Ten patients, ranging in age from 18 to 64, were studied; 8 were women. All were psychotic, but the type and severity of the mental disease varied. None had evidence of impairment of cardiac, renal or thyroid function. The method used was that previously described1 and consisted in measurements over a period of fifteen minutes of the areas of wheals made by injecting a 1 per cent solution of Evans blue (T 1824). One wheal was made

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