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June 1950


Author Affiliations


From the Department of Neurology, Evanghelismos Hospital.

Arch NeurPsych. 1950;63(6):902-917. doi:10.1001/archneurpsyc.1950.02310240061003

SINCE the first description of ophthalmoplegic migraine, neurologists have been divided into two groups with regard to the nosologic standing of the disease. One group, with Charcot, consider this clinical syndrome a common migraine complicated in some of its attacks with ophthalmoplegia; the other group, with Möbius, consider it a relapsing ophthalmoplegia accompanied with cephalalgia and vomiting, a condition quite distinct from migraine.

As a result of the many cases that have been studied and the better knowledge of the migrainous syndrome in general, it is possible to form a more informed opinion of the question, which, according to Charcot, "is, and will perhaps long remain, under study." It is to this revision that I wish to contribute by bringing my observations on the cases of ophthalmoplegic migraine which I have had the opportunity of studying during the past twelve years. Their study leads to certain pathogenic considerations, and particularly