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August 1950

Morgagni's Syndrome.

Arch NeurPsych. 1950;64(2):309-310. doi:10.1001/archneurpsyc.1950.02310260147013

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The symptom complex of hyperostosis frontalis interna, virilism and obesity is referred to by Henschen as Morgagni's syndrome. The term syndrome is significant, since the author does not claim that the constellation of symptoms constitutes a disease sui generis. The review is complete and thorough. The author approaches the problem through a study of the pathology of the disorder, based on a survey of 1,000 female skulls examined post mortem, with a control examination of the same number of male skulls. He emphasizes the fact that Morgagni's syndrome is a symptom complex occurring very often in women after the menopause, but developing less frequently in younger women. In the necrospy material studied, hyperostosis frontalis interna was observed in about 40 per cent of women after the menopause. Henschen states that the triad of hyperostosis frontalis interna, virilism and obesity belongs to the group of syndromes of the pituitary gland. He