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November 1950

"FALSE" LOCALIZING SIGNS IN INTRACRANIAL TUMOR: Report of a Patient with Left Trigeminal Palsy Due to Right Temporal Meningioma

Author Affiliations


AMA Arch NeurPsych. 1950;64(5):692-698. doi:10.1001/archneurpsyc.1950.02310290088009

"FALSE" localizing signs in patients with intracranial tumor are those which when interpreted as being caused by direct involvement by tumor lead the focal diagnosis into error, owing to the fact that the signs are due to processes operating at a distance from the tumor. As Nielsen1 has said, the signs truly indicate failure of function at their respective sites, and the falsity enters with the interpretation. A sign regarded as false by one generation may lose that designation when the mechanism producing the sign becomes known and the correct significance is attached to it.

The line separating true signs from false signs is sometimes indistinct, and it is not always possible to make rigid distinctions between signs relating to the site of the lesion, signs of a neighborhood nature, due to glial reaction or edema about the lesion or other cause, and signs at a distance, due to