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December 1950

Cerebral Circulation in Health and Disease

AMA Arch NeurPsych. 1950;64(6):904-906. doi:10.1001/archneurpsyc.1950.02310300151021

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This monograph reviews the investigation of cerebral circulation between 1887 and 1949.

The review begins with a summary of the comparative anatomy of cerebral arterial and venous systems of man and laboratory animals as a means of evaluating the application of results obtained in laboratory animals to man.

The chapter on anatomy is followed by a summary of the physiology of cerebral circulation, wherein the author stresses the fact that the blood vessels of the brain possess a capacity for intrinsic control and are subject to all the influences that affect the circulation elsewhere in the body. One finds that the influence of arterial blood pressure on cerebral circulation is not completely clarified, but the preponderance of information indicates intrinsic control, with the circulation of the brain tending to follow passively changes in systemic arterial pressure to a greater extent than that of most other organs. The vasoconstrictor and vasodilator

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