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February 1951

EFFECT OF PREFRONTAL LOBOTOMY ON TEMPERATURE REGULATION IN SCHIZOPHRENIC PATIENTS

AMA Arch NeurPsych. 1951;65(2):197-205. doi:10.1001/archneurpsyc.1951.02320020069007
Abstract

I. COMPARISON OF SCHIZOPHRENIC PATIENTS BEFORE AND AFTER FRONTAL LOBOTOMY  IN RECENT years there has been increasing interest in the physiological aspects of mental disease, with particular attention to the role of the autonomic nervous system. Experience with psychoneurotic illnesses, in which somatic disturbances are associated with emotional tension, has indicated that the autonomic nervous system serves as a connecting link between psychic activity, on the one hand, and visceral function, on the other. This view has been well summarized by Cobb.1 The observation of physiological disturbances in the psychoses, particularly in schizophrenia, points to such a mechanism. Investigators have sought to place this relationship on a sounder foundation by demonstrating its neurophysiological basis. Since the anterior frontal areas of the cerebral cortex are regarded as the seat of higher psychic activity, it becomes important to investigate their influence on the autonomic nervous system. Until recently, the bulk of

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