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March 1952


Author Affiliations


From the Section on Pathologic Anatomy (Dr. Kernohan) and the Section on Neurologic Surgery (Dr. Craig), the Mayo Clinic.

AMA Arch NeurPsych. 1952;67(3):269-282. doi:10.1001/archneurpsyc.1952.02320150002001

THE FIRST report of a tumor in the medulla oblongata was that of Chevalier1 in 1834. Since that initial report there have appeared in the medical literature descriptions of a total of 57 cases of primary tumors of the medulla. Practically all these reports have described single cases or have mentioned the tumors in question incidentally in treatises on other subjects. Only two detailed studies of neoplasms confined to the medulla have been published. The first of these was the report by Sokoloff2 in 1887, who reported a glioma of the medulla oblongata in a 5-year-old boy. He collected seven cases of medullary glioma from the world literature. Chabrol,3 in 1908, was stimulated by an instance of sarcoma of the medulla oblongata, which he had recently observed, to review the subject of tumors of the medulla and to report 90 cases of various types of space-occupying lesions

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