[Skip to Navigation]
Other
August 1952

PRIMARY MALIGNANT MELANOMA OF THE SPINAL CORD

Author Affiliations

SAYRE, PA.; PERRY POINT, MD.

From the Guthrie Clinic (Dr. King) and the Veterans Administration Hospital, Perry Point, Md. (Drs. Chambers and Garey).

AMA Arch NeurPsych. 1952;68(2):266-275. doi:10.1001/archneurpsyc.1952.02320200104012
Abstract

PRIMARY malignant melanoma of the central nervous system is a relatively rare neoplasm. Such a growth arising in the spinal cord is even more unusual. When one is encountered, it is often difficult to tell whether the lesion is secondary to a melanoma elsewhere in the body or whether it has spread from one in some other part of the central nervous system. Since many melanomas are not diagnosed until necropsy, it is sometimes difficult to ascertain just the point within the central nervous system from which the neoplasm arose, since the tumor frequently spreads throughout the subarachnoid space either by direct extension or by "seeding." Sometimes dense and extensive metastases occur throughout the leptomeninges, which have been described as "tumor meningitis." It was Virchow1 who in 1859 first reported a case of primary melanoma sarcomatosis. Since that time occasional reports in the literature have appeared, but the number

Add or change institution
×