THERE are few reports in the literature concerning allergic involvement of the central nervous system in man. Only five cases of papilledema thought to be due to allergic response1 have been reported. There are occasional reports of central-nervous-system reactions to rabies immunization that are probably on an allergic basis.2 Experimental work has suggested that certain of the demyelinating diseases may be allergic in nature.3 A case of central-nervous-system disorder thought to be of allergic origin is reported. This observation suggests that allergy must be considered in the differential diagnosis of that vague group of disturbances classified as pseudotumor or encephalopathy of undetermined cause.
REPORT OF CASE
F. L., a 9-year-old white boy, was admitted to the Children's Hospital on Jan. 22, 1949, with the following pertinent history: He had had bouts of hay fever and sensitivity to certain foods. About 3½ years before admission he had an
DEVANNEY JW, SHEA JH. ALLERGIC ENCEPHALOPATHY WITH PAPILLEDEMA: Report of a Case. AMA Arch NeurPsych. 1952;68(6):791–793. doi:10.1001/archneurpsyc.1952.02320240066006
Customize your JAMA Network experience by selecting one or more topics from the list below.