IN TWO previous papers the hypothesis has been developed that the geographic variations in the incidence of multiple sclerosis are influenced by the average amount of the fat consumed: A high-fat consumption is associated with a high incidence of multiple sclerosis; a low-fat consumption is associated with a low incidence of multiple sclerosis.1 Evidence has also been presented which suggests that the consumption of relatively saturated milk and animal fats is more likely to be associated with a high incidence of multiple sclerosis than is the consumption of unsaturated vegetable and fish oils. In either event fat intake seems to increase the incidence of multiple sclerosis by precipitating the disease in susceptible persons.
With the information at hand it is not possible to prove that the apparent relationship of high-fat consumption to a high incidence of multiple sclerosis is not due to factors other than fat which have the
ROY L. SWANK. TREATMENT OF MULTIPLE SCLEROSIS WITH LOW-FAT DIET. AMA Arch NeurPsych. 1953;69(1):91–103. doi:10.1001/archneurpsyc.1953.02320250097011