A PRELIMINARY report of the use of thiamylal (Surital*) sodium with electroshock was first published from the Ypsilanti State Hospital in 1952.1 Later in the same year Wayne2 reported the use of thiamylal with electroshock in senile patients. The original report from this hospital included 20 patients who had received electroshock with thiamylal for a total of 94 treatments. It was found that the use of the drug shortened the seizure and prevented any significant rise in blood pressure. In 1953 Green and Leiser3 published a further report on the subject. Their findings essentially confirmed ours, and, in addition, they noted a prolongation of the postseizure apnea.
Electroshock with thiamylal has been used here for three years on selected patients. No patient has received the thiamylal injection without indication, as it has been our feeling that the use of any drug with electroshock adds some danger. We
BROWN EO. FURTHER EXPERIENCE IN USE OF THIAMYLAL WITH ELECTROSHOCK. AMA Arch NeurPsych. 1954;72(1):88–91. doi:10.1001/archneurpsyc.1954.02330010090007
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