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September 1954

PROTEOLYTIC ENZYME SYSTEM IN SEXUAL DEVIATES

Author Affiliations

LOS ANGELES

AMA Arch NeurPsych. 1954;72(3):341-347. doi:10.1001/archneurpsyc.1954.02330030075008
Abstract

AS PART of a research program on sexual deviation,* a comparative study of several biochemical measures was made in an attempt to define or differentiate subgroups within a total population of hospitalized male sex offenders. This paper reports the results obtained with one of these measures, a compound or compounds present in blood sera which can be quantitatively evaluated by its inhibitory action on the milk-clotting properties of rennin enzyme.

The metabolic significance of rennin inhibitor has not yet been fully explored. Concentrations in blood serum vary with age and with certain conditions of health and disease. High levels are normally found in children, adolescents, and women during pregnancy.1 Elevations of rennin inhibitor are frequently observed2 in hypertension and asthma and during convalescent periods following acute illness and fractures. In malignant disease3 concentrations of rennin inhibitor tend to drop under conditions of rapid tumor growth, rising to

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