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May 1955

Studies in Schizophrenia: A Multidisciplinary Approach to Mind-Brain Relationships.

AMA Arch NeurPsych. 1955;73(5):595-596. doi:10.1001/archneurpsyc.1955.02330110111018

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Heath has focused attention of psychosurgery on the septal area, that part of the brain lying close to the midline in the neighborhood of the anterior commissure. It has been known for some time that lesions in this area produced considerable apathy and inertia, along with visceral phenomena. The first step was to verify these findings in animals, and then to apply various methods of intervention in schizophrenics with the idea of rousing them from their preoccupations. This is a major study, and the findings bring some support to the idea that in this region is the cephalic representation of the reticular formation, with its alerting response upon stimulation. Many difficulties were encountered in the stereotaxic placement of the electrodes used for stimulation, but the placement was more satisfactory by this means than by direct implantation. Recordings taken from the areas at the base of the brain and from neighboring

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