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June 1955

Papilledema in the Guillain-Barré Syndrome

Author Affiliations

Jerusalem, Israel

From the Departments of Neurology and Ophthalmology, Rothschild-Hadassah-University Hospital and the Hebrew University-Hadassah Medical School.

AMA Arch NeurPsych. 1955;73(6):678-684. doi:10.1001/archneurpsyc.1955.02330120082008

The thinking about the Guillain-Barré syndrome has undergone considerable change since its first description, in 1916, as a syndrome of polyradiculoneuritis with albumino-cytological dissociation ending in recovery. It became apparent that the original description should be broadened, and in 1940 De Jong1 recognized cases with a short duration and a favorable prognosis, cases with a prolonged or chronic course, and, finally, those terminating fatally. Later the bulbar, the cerebellar, and the cerebral forms were described and the involvement of the cranial nerves emphasized. These various forms of the syndrome have been fully reviewed recently by Guillain,2 who described the syndrome originally.

Papilledema is very rarely associated with the Guillain-Barré syndrome, and the literature on this subject was reviewed in 1951 by Drew and Magee,3 who collected nine cases and added another. In some of the cases reviewed the cerebrospinal fluid (C. S. F.) pressure was increased, while

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