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June 1955

A Preliminary Note on the Use of Chlorpromazine with Neuropsychiatric Disorders

Author Affiliations

Gulfport, Miss.

From the Veterans Administration Hospital.

AMA Arch NeurPsych. 1955;73(6):700-701. doi:10.1001/archneurpsyc.1955.02330120104011

Psychiatric history is replete with many and varied claims of a pharmacological cure for mental diseases. However, few of these claims have withstood the test of rigorous experimentation. Probably the outstanding form of this type of treatment in use today is insulin. However, this treatment has its drawbacks in the form of expense, time, and the necessity of constant supervision. Various drugs, such as the barbiturates, have been used to quiet actively disturbed patients, as has electric shock and hibernotherapy.3 All of these forms have their liabilities in requiring constant supervision or in leaving the patient in a comatose state for varying periods and, as a result, less accessible than before administration. The lack of accessibility following these accepted treatments is probably the main criticism to be leveled at them. The treatment quiets the patient temporarily but prevents any immediate further treatment in the form of psychotherapy and does

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