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August 1955

Incidence of Seizures, with EEG Findings, in Prefrontal Lobotomy

Author Affiliations

St. Cloud, Minn.

From the Veterans Administration Hospital (Dr. Klotz and Mr. Lommel). Chief, Acute Intensive Treatment Service (Dr. Klotz).

AMA Arch NeurPsych. 1955;74(2):144-148. doi:10.1001/archneurpsyc.1955.02330140028005

This study endeavors to add further objective data to the incidence and course of seizures as a complication of prefrontal lobotomy, with electroencephalographic (EEG) findings and their relationships to the clinical results.

METHOD  A survey of the occurrence of seizures as to type, time after lobotomy, frequency, and course was made on 193 prefrontal lobotomies in 181 patients from March, 1946, to May, 1954, at the Veterans Administration Hospital, St. Cloud, Minn. Anticonvulsant medication was not given to patients who were seizure-free prior to the operation unless the convulsions occurred at a minimum of three regular intervals or were persistent. The EEG's were taken before and within 10 days after the lobotomy. Thence they were taken serially, insofar as possible, at intervals of a month for six months and at six-month intervals thereafter. The recordings were made on a Grass machine with monopolar leads on six channels to December, 1953,