During an investigation of various developmental and pathologic changes in the septum pellucidum, it was decided to correlate neoplasms involving the septum pellucidum with clinical findings to see whether any definite syndrome might evolve. When available, electroencephalograms also were studied to see whether they might be of any localizing value.
Puusepp is credited by French and Bucy1 with the first attempt at resection of the septum pellucidum, in 1942. However, Riskaer2 pointed out that careful examination of their report reveals that the three tumors in question did not originate in the septum pellucidum but were tumors of the frontal lobe that merely invaded the septum. Riskaer reported on two astrocytomas of the septum pellucidum for which operations were done successfully in 1941. This report was not mentioned by French and Bucy or by Chusid and de Gutiérrez-Mahoney.3
In 1948 French and Bucy reviewed the literature dealing with
HUGHES RA, KERNOHAN JW, CRAIG WM. Iumors of the Septum Pellucidum. AMA Arch NeurPsych. 1955;74(3):253–258. doi:10.1001/archneurpsyc.1955.02330150019003
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