A neurological service is often confronted by a patient who has increased intracranial pressure without any localizing abnormality evident on neurological examination. A common tendency is to suspect that such a patient has either "a midline obstructive lesion" or the syndrome that has been called "serous meningitis," "cerebral pseudotumor," or "meningeal hydrops." In our experience, however, a lateralized mass was frequently found despite the absence of focal neurological signs.
In view of this disparity, it was decided to make a systematic study of the problem.
A survey was made of the operating room records at the Neurological Institute of New York from January, 1945, to September, 1953. The case histories of all patients who underwent ventriculography and/or craniotomy were reviewed. Excluded from the study were (1) infants who were under the age of one year (congenital hydrocephalus eliminated for the most part); (2) patients on whom operations had been
BERG L, ROSOMOFF HL, ARONSON N, SILBERMANN M, POOL JL. The Syndrome of Increased Intracranial Pressure Without Localizing Signs. AMA Arch NeurPsych. 1955;74(5):498–505. doi:https://doi.org/10.1001/archneurpsyc.1955.02330170032005
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