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November 1955

Mongolism and Convulsive Seizures

Author Affiliations

Los Angeles; San Francisco

From the University of California School of Medicine, the Sonoma State Hospital, and the State of California Department of Mental Hygiene, The Langley Porter Clinic.

AMA Arch NeurPsych. 1955;74(5):559-563. doi:10.1001/archneurpsyc.1955.02330170093016

It has been recognized for many years that mongoloid mental defectives rarely have epileptic seizures. Though all who have had experience in caring for large groups of mental defectives are aware of the low incidence of convulsions in this group, there appears to have been little discussion of this finding in the literature. Kirman1 described in some detail the case history of a patient with mongolism who developed seizures after a cerebral vascular accident with consequent extensive, but lateralized, cerebral atrophy. He also stated that in his own series of 91 cases of mongolism the patient with the vascular accident was the only one with seizures. The standard reference works either do not mention the incidence of convulsions among this group or state that it approaches that in the normal population. This rarity of seizures in mongolism is surprising if it is true that the neuropathology of this disease

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