In 1942 Stout and Murray1 described a group of vascular neoplasms which they suggested were derived from the capillary pericytes of Zimmermann,2 and classified these tumors as hemangiopericytomas. The histologic appearance of the hemangiopericytoma was distinct from that of the hemangioma, hemangioendothelioma, or glomus tumor, and its identification was facilitated by the use of silver impregnation techniques for the demonstration of reticulum.
The hemangiopericytoma is not rare, despite the relative paucity of recorded examples of such tumors. Reports have indicated that they are found with equal frequency in both sexes and in all age groups. Approximately one-third of the cases have demonstrated malignant characteristics, as evidenced by distant metastases or local invasion and recurrence.3 Such neoplasms have been observed in a wide variety of locations, as might be expected from the ubiquitous distribution of blood vessels throughout the body. Although perhaps most frequent in the soft tissues,
FISHER ER, DAVIS JS, LEMMEN LJ. Meningeal Hemangiopericytoma. AMA Arch NeurPsych. 1958;79(1):40–45. doi:https://doi.org/10.1001/archneurpsyc.1958.02340010058004
Customize your JAMA Network experience by selecting one or more topics from the list below.