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April 1959

Boeck's Sarcoid Simulating a Brain Tumor

Author Affiliations

Brooklyn

From the Section of Neurology, Veterans Administration Hospital.

AMA Arch NeurPsych. 1959;81(4):419-423. doi:10.1001/archneurpsyc.1959.02340160017003
Abstract

Introduction  Invasion of the nervous system by Boeck's sarcoid occurs not infrequently. Most commonly the peripheral and cranial nerves are affected.2 The central nervous system is less frequently involved. When it is involved, it may be invaded by a diffuse granulomatous leptomeningitis, most commonly at the base of the brain,11,14 or the disease may occur as a diffuse perivascular infiltration within the brain substance,11 or, rarely, the picture may be that of an acute or a chronic meningoencephalitis.9 Not uncommonly, sarcoid lesions may invade the pituitary gland, giving rise to diabetes insipidus.10,14 The following case is of interest in that it presented a clinical picture of a brain tumor, and at craniotomy a granulomatous mass, resembling a meningioma, was found.

Report of a Case  The patient, a 39-year-old Negro male office worker, was born in New York City of British West Indian parentage. He had

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