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April 1959

Psychoses, Intracranial Neoplasms, and Genetics

Author Affiliations

Iowa City

From the Department of Surgery, State University of Iowa College of Medicine, and the Department of Mathematics and Astronomy, State University of Iowa, and Mount Pleasant and Independence Mental Health Institutes, State of Iowa.

AMA Arch NeurPsych. 1959;81(4):480-485. doi:10.1001/archneurpsyc.1959.02340160078012

The nature of the association between the ABO blood groups and disease is being investigated in the population of the State of Iowa.1 The demonstration of statistically significant associations between the ABO blood groups and several diseases suggests that the ABO blood groups may be a tool useful in investigation of genetic factors in still other disorders. This paper is a report of the findings in patients with psychoses and intracranial neoplasms (brain tumors).

Materials and Methods  The ABO blood types of the patients resident in Mount Pleasant and Independence Mental Health Institutes were determined by the research team, using a slide technique. The patient's blood type, diagnosis, and other relevant information abstracted from the patient's chart were recorded on punch cards. The diagnoses had previously been established by staff members of the Mental Health Institutes and were based upon the standard nomenclature of mental disorders recommended by the