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June 1959

Production of Hydrocephalus by Increased Cephalic-Venous Pressure

Author Affiliations


From the Neurosurgical Research Laboratory of the Children's Medical Center.

AMA Arch NeurPsych. 1959;81(6):693-698. doi:10.1001/archneurpsyc.1959.02340180027004

The relationship of increased cerebral venous pressure to ventricular enlargement and hydrocephalus has never been satisfactorily worked out. The interdependence of intracranial pressure and cerebral venous pressure has been recognized both in clinical problems and in experimental studies, but the possibility of cerebral venous pressure as a primary cause of ventricular enlargement has remained a controversial issue.

Dandy2 stated that the occlusion of the vein of Galen would cause hydrocephalus. Others have tried this and other types of experimental venous occlusions, with varying results. Russell,4 in her monograph on hydrocephalus, reviewed much of this work, including some experimental work of her own, and concluded that, while hydrocephalus had apparently been produced in some instances, the results were, in general, equivocal. These experimental attempts to produce hydrocephalus from increased venous pressure were all based upon local occlusion of a cerebral vein or dural sinus. This allowed the possibility that

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