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May 5, 1999

Prostatectomy, External Beam Radiation Therapy, or Brachytherapy for Localized Prostate Cancer

Author Affiliations

Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor

JAMA. 1999;281(17):1583-1586. doi:10-1001/pubs.JAMA-ISSN-0098-7484-281-17-jbk0505

To the Editor: The retrospective study by Dr D'Amico and colleagues1 offers the first published attempt to compare treatment methods for localized prostate cancer using similar outcomes. However, as pointed out,2 problems comparing radiation and surgical literature arise from the definition of failure. The data of D'Amico et al are an affirmation that all modalities are effective for localized disease, yet the authors focus on the brachytherapy component, despite acknowledging the inherent limitations of their study.