Copyright 1999 American Medical Association.
All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1999
To the Editor: Dr Patchell and
colleagues1 have shown that following surgical excision of
a solitary brain metastasis, postoperative radiotherapy delays
recurrence in the brain but does not increase median survival or the
number of long-term survivors (7/46 in the observation group vs 6/49 in
the irradiated group). The authors have also shown a statistically
significant correlation between the time from diagnosis of the primary
tumor to the development of metastases and the survival time, and a
significantly longer survival time in those patients in the observation
group who died of systemic disease, compared with the much larger
number of patients in the irradiated group who died of systemic
Yaes RJ. Postoperative Radiotherapy for Single Brain Metastases. JAMA. 1999;281(18):1695. doi:10-1001/pubs.JAMA-ISSN-0098-7484-281-18-jac90004
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