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August 11, 1999

Correcting the Odds Ratio in Cohort Studies of Common Outcomes

Author Affiliations

Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor

JAMA. 1999;282(6):529. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-6-jbk0811

To the Editor: The article by Drs Zhang and Yu1 addresses a common mistake—using the odds ratio (OR) to estimate relative risk (RR) when the disease being studied is common (>10%).1 The authors' proposed solution is intriguing; however, it may be an oversimplification.