Margaret A.WinkerMD, Deputy EditorIndividualAuthorPhil B.FontanarosaMD, Interim CoeditorIndividualAuthor
To the Editor: Dr He and colleagues1 claim that the overall benefit of aspirin use on
myocardial infarction and ischemic stroke outweighs its risk of hemorrhagic
stroke in most populations. However, they also suggest that the risk-benefit
ratio of aspirin treatment for prevention of cardiovascular disease in populations
with a high risk of hemorrhagic stroke should be addressed in subsequent studies.
Tokuda Y, Kato J. Aspirin and Risk of Hemorrhagic Stroke. JAMA. 1999;282(8):731–733. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-8-jbk0825