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December 1, 1999

Antibiotic Use and Risk of Myocardial Infarction

Author Affiliations

Phil B.FontanarosaMD, Interim CoeditorIndividualAuthorMargaret A.WinkerMD, Deputy EditorIndividualAuthorStephenLurieMD PhD, Fishbein FellowIndividualAuthor

JAMA. 1999;282(21):1997-1999. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-21-jbk1201

To the Editor: The study by Dr Meier and colleagues1 concluded that there was a significantly lower chance that patients with an episode of AMI were prescribed certain antibiotics 3 years prior to the episode than matched controls. The authors give several reasons why their findings should not lead physicians to prescribe antibiotics to prevent myocardial infarction at this time. An important reason not given was the number of comparisons made.