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December 1, 1999

Antibiotic Use and Risk of Myocardial Infarction

Author Affiliations

Phil B.FontanarosaMD, Interim CoeditorIndividualAuthorMargaret A.WinkerMD, Deputy EditorIndividualAuthorStephenLurieMD PhD, Fishbein FellowIndividualAuthor

JAMA. 1999;282(21):1997-1999. doi:10-1001/pubs.JAMA-ISSN-0098-7484-282-21-jbk1201

To the Editor: The possible association of infection and atherosclerosis remains controversial. It is extremely difficult to retrospectively assume that an effect seen with an antibiotic is secondary to "treating" a specific organism as implied in the article by Meier and colleagues.1 This is especially true for C pneumoniae, for which the data on treatment are extremely limited and are further complicated by the lack of standardized diagnostic methods.