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January 26, 2000

Predicting Cardiovascular Risk Using Ambulatory Blood Pressure—Reply

Author Affiliations

Phil B.FontanarosaMD, Deputy EditorIndividualAuthorMargaret A.WinkerMD, Deputy EditorIndividualAuthorStephen J.LurieMD, PhD, Fishbein FellowIndividualAuthor

JAMA. 2000;283(4):475-476. doi:10.1001/jama.283.4.475

In Reply: The clarifications provided by Drs Ohkubo and Imai on the Ohasama study,1 the first population-based study on the prognostic significance of ambulatory BP, are consistent with our results of the Systolic Hypertension in Europe Trial (Syst-Eur).2 Both studies demonstrated that even after adjustment for conventional BP measurements, the 24-hour BP remained linearly and significantly correlated with cardiovascular mortality. We agree with the proposition that 24-hour ambulatory BP, irrespective of the population studied, is a better predictor of cardiovascular risk than conventional BP.