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May 3, 2000

Chronic Systemic Inflammation in Overweight and Obese Adults

Author Affiliations

Phil B.FontanarosaMD, Deputy EditorIndividualAuthorStephen J.LurieMD, PhD, Contributing EditorIndividualAuthor

JAMA. 2000;283(17):2235-2236. doi:10.1001/jama.283.17.2235

To the Editor: Dr Visser and colleagues1 reported elevated levels of C-reactive protein (CRP) in otherwise healthy overweight and obese individuals, suggesting a state of chronic low-grade systemic inflammation. The authors, in their rationale for measuring CRP, cited studies showing an association between adipose tissue and the proinflammatory cytokine interleukin 6 (IL-6), but they did not measure serum concentrations of IL-6.

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