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June 7, 2000

False-Positive Tuberculin Skin Test Results Among Health Care Workers

Author Affiliations

Phil B.FontanarosaMD, Deputy EditorIndividualAuthorStephen J.LurieMD, PhD, Contributing EditorIndividualAuthor

JAMA. 2000;283(21):2793. doi:10.1001/jama.283.21.2787

To the Editor: Two different commercial tuberculin reagents are available in the United States. Villarino et al1 concluded that "both Aplisol [Parkdale Pharmaceuticals, Rochester, Mich] and Tubersol [Pasteur Mérieux Connaught USA, Swiftwater, Pa] will correctly classify comparable numbers of persons not infected with M[ycobacterium] tuberculosis and that the choice of product used for [tuberculin] skin testing has little effect on test performance." An experience at our institution with false-positive tuberculin skin test (TST) results among a group of health care workers, which was associated with the use of Aplisol, contradicts these conclusions.