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July 12, 2000

Exercise Regimens for Men With HIV—Reply

Author Affiliations

Stephen J.LurieMD, PhD, Contributing EditorIndividualAuthor

JAMA. 2000;284(2):175-176. doi:10.1001/jama.284.2.175

In Reply: The use of single vs multiple sets of repetitions for resistance exercise training is a controversial issue in the design of resistance training programs. The exercise regimen used in our study was developed in 1995 using multiset and periodization models based on established sources,1 as well as our successful experience with a similar training program in healthy men.2 In that study, the periodized, thrice-weekly, resistance training was safe and effective in substantially increasing fat-free mass and maximal strength in healthy men. Similarly, in HIV-infected men, use of a multiset, periodized, thrice-weekly resistance training protocol was associated with significant gains in fat-free mass and maximal strength.