Stephen J.LurieMD, PhD, Contributing EditorIndividualAuthor
To the Editor: The efficacy of highly active
antiretroviral therapy (HAART) in the treatment of human immunodeficiency
virus (HIV) infection has been demonstrated in a number of clinical reports.1 However, current regimens are complex and poor
adherence to therapy is the main cause of both treatment failure and emergence
of drug resistance.2 Adherence to multidose
treatment regimens may be more difficult in certain settings, such as prison.3 Herein we report data from HIV-positive prisoners
treated using a directly observed therapy (DOT) program.4
To our knowledge, DOT for HIV infection has not been evaluated in this setting.
Fontanarosa PB, Babudieri S, Aceti A, D'Offizi GP, Carbonara S, Starnini G. Directly Observed Therapy to Treat HIV Infection in Prisoners. JAMA. 2000;284(2):179–180. doi:10.1001/jama.284.2.175
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