[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
August 9, 2000

Estrogen-Progestin Replacement and Risk of Breast Cancer

Author Affiliations

Stephen J.LurieMD, PhD, Contributing EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor

JAMA. 2000;284(6):691-694. doi:10.1001/jama.284.6.691

To the Editor: Dr Schairer and colleagues1 reported an RR for breast cancer of 1.4 for women who had used estrogen-progestin replacement therapy for 4 years compared with women who had never used estrogen or progestin therapy. This equates to a 40% increase in the risk of breast cancer, a figure that was seized on and widely reported by the media.