Stephen J.LurieMD, PhD, Contributing EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor
In Reply: The comments of Dr Annitto and Ms
Kelly aptly illustrate the diversity of views about methadone treatment within
the clinical community. Some may find this diversity surprising, given the
evidence indicating the clinical efficacy of methadone maintenance for the
treatment of opioid dependence.1 Annitto
appears to have misconstrued the findings of our study to indicate that there
were no differences between treatment conditions on important variables such
as heroin use and psychosocial functioning. Our data indicate that patients
in the methadone maintenance treatment group showed significantly less heroin
use and reported less human immunodeficency virus (HIV) risk–related
drug use behavior. In contrast, as far as we could determine, there are no
controlled studies of 12-step programs for the treatment of opioid addiction.
Therefore, their efficacy for the treatment of this disorder is unknown.
Sees KL, Delucchi KL, Masson C, et al. Methadone Maintenance for Opioid Dependence—Reply. JAMA. 2000;284(6):694–695. doi:10.1001/jama.284.6.691
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