Stephen J.LurieMD, PhD, Contributing EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor
To the Editor: The incidence of esophageal
and gastric cardia adenocarcinoma is increasing in Western Europe and the
United States.1 Survival rates2
are substantially improved by early tumor detection.3
Therefore, it seems important to identify high-risk persons in whom endoscopic
surveillance might be warranted. Recently, symptomatic reflux4
and obesity5 were found to be strong independent
risk factors for these tumors, particularly for esophageal adenocarcinoma.4,5 Endoscopic surveillance of persons
with reflux has been suggested,6 but the
benefits and efforts are unknown.
Lagergren J, Ye W, Bergström R, Nyrén O. Utility of Endoscopic Screening for Upper Gastrointestinal Adenocarcinoma. JAMA. 2000;284(8):961–962. doi:10.1001/jama.284.8.956
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