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September 27, 2000

Postexposure Prophylaxis for HIV After Sexual Assault

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor

JAMA. 2000;284(12):1516-1518. doi:10.1001/jama.284.12.1512

To the Editor: Sexual assault nurse examiners working for the San Francisco Department of Public Health at San Francisco General Hospital have offered human immunodeficiency virus (HIV) postexposure prophylaxis (PEP) to survivors of sexual assault since April 1998. Survivors who choose to initiate PEP are given zidovudine (300 mg, twice daily) and lamivudine (150 mg, twice daily) in a combination pill for 10 days. At a follow-up visit 7 to 10 days later, an additional 18 days of the same PEP medications are offered. However, characteristics of those who choose to initiate and complete PEP have not been well described.