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October 25, 2000

Do Increased 5-Year Survival Rates in Prostate Cancer Indicate Better Outcomes?—Reply

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor

JAMA. 2000;284(16):2053-2055. doi:10.1001/jama.284.16.2053

To the Editor: Dr Welch and colleagues1 argue that, because of lead time bias, men diagnosed with prostate cancer might not be living longer and instead are only being diagnosed earlier. Increasing 5-year survival rates thus may not reflect reduced disease burden and should not be taken as evidence of improved prevention, screening, or therapy.

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