Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor
To the Editor: Dr Welch and colleagues1 argue that, because of lead time bias, men diagnosed
with prostate cancer might not be living longer and instead are only being
diagnosed earlier. Increasing 5-year survival rates thus may not reflect reduced
disease burden and should not be taken as evidence of improved prevention,
screening, or therapy.
Donnelly B. Do Increased 5-Year Survival Rates in Prostate Cancer Indicate Better Outcomes?—Reply. JAMA. 2000;284(16):2053–2055. doi:10.1001/jama.284.16.2053